Yuanzhe Zhou (周源哲)


I am a postdoctoral fellow in the Department of Physics and Astronomy at University of Missouri - Columbia. My primary research interests are computational modeling of RNA-targeted drug discovery. My recent projects are focused on developing data-driven machine learning and optimization algorithms to elucidate complex relationships between upon ligand binding . I obtained my Ph.D. in Physics from the University of Missouri - Columbia in 2016 under the supervision of Prof. Shi-Jie Chen.
Research Interests

Biophysics
RNA-ligand interaction
Major Projects (More Description)

☆ Empirical energy/statistical potential based scoring functions for
    1. Ligand binding mode prediction
    2. RNA-ligand virtual screening

☆ MgNet, a convolutional neural network (CNN) model for predicting Mg2+ binding sites in RNAs
Education

PhD in Physics, University of Missouri - Columbia, Columbia, USA, 2021
BS in Physics, Southern University of Science and Technology (SUSTech), Shenzhen, China, 2016

© Yuanzhe Zhou,